Are you ready to turn cutting-edge biologics science into reliable, high-quality medicines for people living with rare and devastating conditions? Do you thrive on owning a process end-to-end and mentoring others on shift to deliver consistent results?

As a Bio Process Technician, you will be part of a shift-based manufacturing team that transforms cell culture and purification expertise into safe, compliant batches that reach patients who rely on them. Your precision, judgment, and leadership will keep production on-spec, documentation immaculate, and deviations swiftly understood and addressed. You will work with colleagues across quality, technical services, and automation to keep equipment ready, processes robust, and supply flowing.

Accountabilities:
- End-to-End Manufacturing Execution: Perform cell culture, media preparation, purification, buffer preparation, and equipment preparation independently to deliver batches on time and in full.
- Documentation Excellence: Execute all tasks in a cGMP environment with meticulous attention to SOPs and batch records to ensure audit-ready, right-first-time documentation.
- Area Specialism and Leadership: Develop subject matter expertise in at least one operational area and serve as a Champion to drive standards, improvements, and consistency within the shift team.
- Deviation Management and Improvement: Assist with investigation of operational deviations via the quality tracking system (QTS), identify root causes, and implement corrective actions that strengthen the process.
- Training and Knowledge Transfer: Coach and train colleagues on SOPs, process execution, and equipment operation; be a trusted source of knowledge on shift.
- Equipment and Facility Readiness: Support facility/equipment start-up and validation activities; contribute to equipment installation, start-up, operation, and troubleshooting to maintain state of control and enable new product introductions.
- Cross-Functional Engagement: Partner with Technical Services, QA, and Automation to resolve issues quickly and maintain continuous manufacturing performance.
- Shift Ownership and Communication: Organize local work teams, set priorities according to the schedule, and deliver clear, concise shift handovers and reports to site leadership and technical stakeholders.
- Lean and Safety Mindset: Lead by example in EHS and GMP while applying lean thinking to eliminate waste, simplify workflows, and increase productivity.

Essential Skills/Experience:
- Trained and competent to independently perform core biologics production tasks, including cell culture, media preparation, purification, buffer preparation, and equipment preparation.
- Proven execution in a cGMP environment with excellent attention to detail and high-quality documentation aligned to SOPs and batch records.
- High level of subject matter expertise in at least one manufacturing area and effective process leadership within that area.
- Ability to anticipate and troubleshoot operational issues; effective interface with Manufacturing Control Systems (MCS).
- Experience assisting in deviation investigations through a quality tracking system (e.g., QTS) and engaging relevant stakeholders to resolve issues.
- Ability to train colleagues in SOPs, process execution, and equipment operation, and to contribute to creation and maintenance of area SOPs and batch records.
- Demonstrated lean mindset; positive example in EHS, GMP, and productivity on shift.
- Willingness and ability to work shifts, including weekends and periodic rotation between day and night shifts, based on business needs.
- Capability to prepare and deliver shift handovers and report out to leadership and technical/engineering stakeholders.
- Ability to organize local work teams, identify priorities, and ensure the schedule is executed.

Desirable Skills/Experience:
- Experience acting as an area lead or Champion to drive improvements and excellence within a manufacturing operation.
- Experience leading and owning investigations and change controls.
- Exposure to facility and equipment start-up and validation, with practical input on equipment installation, operation, and troubleshooting to support new product introductions.
- Strong cross-functional collaboration with Technical Services, QA, and Automation to resolve complex issues.

Why AstraZeneca:
Join a team where your craftsmanship in the suite directly improves the lives of people who have few other options. We bring unexpected teams together—manufacturing, quality, engineering—in the same room to solve tough problems with urgency and care. With the pace and autonomy of a biotech and the strength of a global biopharma, you will work with modern platforms and systems, learn from generous experts, and see your ideas quickly tested on the floor. We value kindness alongside ambition, and we connect your growth to a clear purpose: delivering life-changing therapies to those who need them most.

Call to Action:
If you are ready to lead on shift, elevate standards, and see the impact of your work reach patients, step forward today and help us make every batch count!

Date Posted

30-Jan-2026

Closing Date

13-Feb-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Bio-Process Technician - 12 Month Fixed Term Contract (24/7 Shift)

Job Description