Senior Scientist (Chemistry), Chemical Development

Location: Dublin

Competitive Salary and Benefits

Accountabilities:
As a Senior Scientist, you will be responsible for supporting the technical contribution to transfer, maintain and optimise supply for one or more AstraZeneca commercial products. You will identify, develop and implement process improvements for both launch and commercial products through the use of existing and cutting-edge technologies. You will also provide expert technical input through laboratory experimentation, in-silico modelling and direct manufacturing support at our internal AZ API manufacturing site in Dublin. Your role will also involve contribution to the CMC components of regulatory submissions and preparation of successful query responses over the commercial life of a product.

Essential Skills/Experience:
- BSc/PhD level education in a relevant discipline and experience working within a Research & Development or Manufacturing environment, within the pharmaceutical industry.
- Technical expertise and understanding of practical synthetic organic chemistry spanning across both lab and manufacture.

- Experience in the Tech Transfer of pharmaceutical small molecule Drug Substance processes

- Background in dealing with the challenges of both the scale up and scale down of processes
- A good understanding of the overall drug development process from discovery through to launch.
- A thorough understanding of the principles and management of SHE and cGMP.

- Excellent communication and strategic influencing skills across interfaces of discipline, culture, and expertise both internally and externally.

- Proven problem solver with in depth technical skills.

- Proficiency in the use of statistics to understand data.

- Ability to think and operate across functional boundaries, challenge the status quo and seek opportunities for business improvement.

Desirable Skills/Experience:
- Experience of delivering CMC content or contributions to regulatory filings throughout the life cycle of process development, in the pharmaceutical industry.

- Experience working within a Research & Development and Manufacturing environment in the pharmaceutical industry

- Experience of technical supervision and leading small teams of people or scientific projects.

- Experience of late stage development or commercial supply with a background in a process chemistry skill group

- Experience of working across skillsets (e.g. with chemists, analysts and physical properties experts).

Why AstraZeneca?

At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development!

So, What's Next

If you are already imagining yourself joining our team, Good, because we can’t wait to hear from you!

Find out more on Social Media:

LinkedIn https://www.linkedin.com/company/1603/
Facebook https://www.facebook.com/astrazenecacareers/
Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
About Operations https://www.youtube.com/watch?v=gak5Ham8oUw

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Date Posted

14-Jan-2026

Closing Date

27-Jan-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Senior Scientist (Chemistry), Chemical Development

Job Description